Pseudomonas aeruginosa

The Bacteria

Pseudomonas aeruginosa is a highly common, Gram-negative, rod-shaped bacterium that is noted for its ability to cause disease in animals, humans and plants, its versatility in adapting and thriving in nearly any environment, and its intrinsic resistance to antibiotics. An opportunistic pathogen, it is responsible for many nosocomial infections in humans, including: urinary tract infections, respiratory system infections, gastrointestinal infections, bacteremia, soft tissue infections, bone and joint infections, and a variety of systemic infections. Pseudomonas aeruginosa is often found on various medical devices including catheters and ventilators, and contributes to cross-infections in ICU units at hospitals and in clinics. Especially at risk are those patients who are hospitalized, having highly suppressed immune systems due to severe burns, cancer, AIDS, and those with Cystic Fibrosis. In such cases, the mortality rate is close to 50 percent.

The Problem

Pseudomonas aeruginosa is inherently resistant to a wide variety of antibiotics and demonstrates the ability to acquire further resistance through mutation or gene transfer. This is a formidable characteristic, and of the utmost concern to finding an effective treatment for infections caused by Pseudomonas aeruginosa. Therefore, rapid detection and testing is imperative for reducing antibiotic resistant strains and death, and for treating those who are most susceptible to infection by this common bacteria.

Several testing methods currently exist to detect Pseudomonas aeruginosa. Of those, molecular techniques such as DNA extraction and PCR are garnering attention for their rapid results. However, these tests do not provide for the detection of viable microorganisms. In addition, when the need for expensive equipment and specialized labs and training are factored in, PCR for Pseudomonas aeruginosa comes at a significant cost.

The NanoLogix Solution - Live-threat microorganism detection in 5 hours

Using innovative, rapid detection technology based on the widely accepted and economical Petri-dish, NanoLogix is able to grow micro-colonies and return live-cell microoragnism results in approximately 5 hours. Fast, accurate and trusted results are essential to reducing the threat of antibiotic resistance from the ubiquitous Pseudomonas aeruginosa and to preventing fatalities.